Top 33 AI startups in Boston
May 22, 2026
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30
1
Funding: $468.9M
Tomorrow.io develops an AI weather prediction platform and operates its own satellite constellation, which uses a unique, reconfigurable radar to collect data on a wide range of geophysical variables. Tomorrow.io's microsonde satellites measure atmospheric temperature, water vapor and precipitation - even through cloud cover. High-resolution precipitation data collection with an average revisit rate of one hour allows the company to achieve a new level of understanding and forecasting of hurricanes, floods, landslides, wildfires, and droughts. AI model integrates satellite and global data, enabling more accurate real-time forecasts in areas traditionally lacking reliable meteorological data.
Tomorrow.io develops an AI weather prediction platform and operates its own satellite constellation, which uses a unique, reconfigurable radar to collect data on a wide range of geophysical variables. Tomorrow.io's microsonde satellites measure atmospheric temperature, water vapor and precipitation - even through cloud cover. High-resolution precipitation data collection with an average revisit rate of one hour allows the company to achieve a new level of understanding and forecasting of hurricanes, floods, landslides, wildfires, and droughts. AI model integrates satellite and global data, enabling more accurate real-time forecasts in areas traditionally lacking reliable meteorological data.
2
Funding: $1.1B
DataRobot has pioneered some of the most important applied technological advancements in AI and machine learning, from inventing AutoML and Automated Time Series to trailblazing MLOps and generative AI. Its platform and solutions integrate into core business processes so teams can build, operate and govern AI at scale. Using the platform companies can develop, deliver, and govern agentic AI apps with a production-grade sandbox, library of tool accelerators, and comprehensive platform.
DataRobot has pioneered some of the most important applied technological advancements in AI and machine learning, from inventing AutoML and Automated Time Series to trailblazing MLOps and generative AI. Its platform and solutions integrate into core business processes so teams can build, operate and govern AI at scale. Using the platform companies can develop, deliver, and govern agentic AI apps with a production-grade sandbox, library of tool accelerators, and comprehensive platform.
3
Funding: $970.6M
Complete next-generation endpoint security: EDR, NGAV, anti-ransomware, fileless malware protection, and managed services powered by a proprietary AI hunting engine. Cybereason uses machine learning to increase the number of endpoints a single analyst can manage across a network of distributed resources
Complete next-generation endpoint security: EDR, NGAV, anti-ransomware, fileless malware protection, and managed services powered by a proprietary AI hunting engine. Cybereason uses machine learning to increase the number of endpoints a single analyst can manage across a network of distributed resources
4
Funding: $822M
Lightmatter uses photonic computing to accelerate computation and communication between chips in cloud AI systems. The company's first two products are Passage chips, which utilize both photons and electrons to improve operational efficiency. They combine the computational tasks that electrons excel at (such as memory) with those that light excels at (such as performing massive matrix multiplications in deep learning models). Photonics enables multiple computations to be performed simultaneously because data arrives as light of different colors. This increases the number of operations per unit area and reuses existing hardware, improving energy efficiency. Passage takes advantage of the bandwidth of light to connect processors, similar to how fiber optic cables use light to transmit data over long distances. This allows disparate chips to function as a single processor.
Lightmatter uses photonic computing to accelerate computation and communication between chips in cloud AI systems. The company's first two products are Passage chips, which utilize both photons and electrons to improve operational efficiency. They combine the computational tasks that electrons excel at (such as memory) with those that light excels at (such as performing massive matrix multiplications in deep learning models). Photonics enables multiple computations to be performed simultaneously because data arrives as light of different colors. This increases the number of operations per unit area and reuses existing hardware, improving energy efficiency. Passage takes advantage of the bandwidth of light to connect processors, similar to how fiber optic cables use light to transmit data over long distances. This allows disparate chips to function as a single processor.
5
Funding: $463.6M
Biofourmis is reinventing remote patient monitoring by detecting personalized patterns predictive of patient’s health deterioration
Biofourmis is reinventing remote patient monitoring by detecting personalized patterns predictive of patient’s health deterioration
6
Funding: $387.5M
Caresyntax is a digital surgery platform that uses proprietary software and AI to deliver actionable insights to improve patient outcomes.
Caresyntax is a digital surgery platform that uses proprietary software and AI to deliver actionable insights to improve patient outcomes.
7
Funding: $355.2M
PathAI's goal is to improve cancer diagnosis using artificial intelligence. PathAI’s services solve the most challenging pathology problems faced by the research and pharmaceutical industry.
PathAI's goal is to improve cancer diagnosis using artificial intelligence. PathAI’s services solve the most challenging pathology problems faced by the research and pharmaceutical industry.
8
Funding: $265.2M
Sophia Genetics developed SOPHiA, a collective artificial intelligence for clinical genomics, helping healthcare professionals better diagnose and treat patients.
Sophia Genetics developed SOPHiA, a collective artificial intelligence for clinical genomics, helping healthcare professionals better diagnose and treat patients.
9
Funding: $247M
QuEra Computing is a neutral-atoms-based quantum computing startup, located in Boston, near Harvard University.
QuEra Computing is a neutral-atoms-based quantum computing startup, located in Boston, near Harvard University.
10
Funding: $149.5M
Rethink Robotics helps manufacturers meet the challenges of an agile economy with an integrated workforce, combining trainable, safe and cost-effective robots with skilled labor. Its Baxter robot, driven by Intera, an advanced software platform, gives world-class manufacturers and distributors in automotive, plastics, consumer goods, electronics and more, a workforce multiplier that optimizes labor.
Rethink Robotics helps manufacturers meet the challenges of an agile economy with an integrated workforce, combining trainable, safe and cost-effective robots with skilled labor. Its Baxter robot, driven by Intera, an advanced software platform, gives world-class manufacturers and distributors in automotive, plastics, consumer goods, electronics and more, a workforce multiplier that optimizes labor.
11
Funding: $133.5M
Merlin Labs develops autonomous flight system designed to be installed in existing aircraft.
Merlin Labs develops autonomous flight system designed to be installed in existing aircraft.
12
Funding: $123.2M
Gradient AI provides underwriting and claims management solutions for group health, property, casualty, and workers' compensation insurers.
Gradient AI provides underwriting and claims management solutions for group health, property, casualty, and workers' compensation insurers.
13
Funding: $118.2M
Realtime Robotics developer of specialized processor for generating safe robot motion plans in micro-seconds.
Realtime Robotics developer of specialized processor for generating safe robot motion plans in micro-seconds.
14
Funding: $100.4M
Activ Surgical is building a hardware-agnostic platform to enable autonomous and collaborative surgery through the integration of computer vision, artificial intelligence and robotics.
Activ Surgical is building a hardware-agnostic platform to enable autonomous and collaborative surgery through the integration of computer vision, artificial intelligence and robotics.
15
Funding: $93.2M
The primary device of Current’s monitoring platform is an FDA-cleared upper-arm wearable that tracks skin temperature, pulse rate, oxygen saturation, movement and other metrics. It uses AI for precise early warning alerts.
The primary device of Current’s monitoring platform is an FDA-cleared upper-arm wearable that tracks skin temperature, pulse rate, oxygen saturation, movement and other metrics. It uses AI for precise early warning alerts.
16
Funding: $93.2M
Snap40 develops a device that monitors users via its single medical-grade wearable device, worn on the upper arm. This includes relative changes in systolic blood pressure, respiratory rate, heart rate, mobility, blood oxygen saturation, and temperature, as well as perspiration and movement levels. Snap40 uses a predictive analytics software platform to identify, in real-time, those who are at risk of health deterioration.
Snap40 develops a device that monitors users via its single medical-grade wearable device, worn on the upper arm. This includes relative changes in systolic blood pressure, respiratory rate, heart rate, mobility, blood oxygen saturation, and temperature, as well as perspiration and movement levels. Snap40 uses a predictive analytics software platform to identify, in real-time, those who are at risk of health deterioration.
17
Funding: $66.5M
Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.
Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.
18
Funding: $57.8M
Neurable produces smart headphones with built-in EEG sensors and AI signal processing system that monitors and analyzes brain activity in real time, thereby implementing a brain-computer interface. The headphones work in tandem with a mobile app that provides cognitive data on mental fatigue, cognitive recovery and concentration, enabling more productive work. Neurable also collaborates with other companies to integrate brain-computer interface capabilities into various devices and systems. Specifically, it has partnered with iMotions - software platform for human behavioral research; MeSpace, which develops and manufactures workstations aimed at enhancing productivity and Healthspan Digital, a precision medicine company focused on longevity, to help professionals assess brain health and cognitive performance.
Neurable produces smart headphones with built-in EEG sensors and AI signal processing system that monitors and analyzes brain activity in real time, thereby implementing a brain-computer interface. The headphones work in tandem with a mobile app that provides cognitive data on mental fatigue, cognitive recovery and concentration, enabling more productive work. Neurable also collaborates with other companies to integrate brain-computer interface capabilities into various devices and systems. Specifically, it has partnered with iMotions - software platform for human behavioral research; MeSpace, which develops and manufactures workstations aimed at enhancing productivity and Healthspan Digital, a precision medicine company focused on longevity, to help professionals assess brain health and cognitive performance.
19
Funding: $44.3M
Sea Machines Robotics builds autonomous control and navigation systems for the commercial marine and boating industries.
Sea Machines Robotics builds autonomous control and navigation systems for the commercial marine and boating industries.
20
Funding: $41.7M
Hi Marley is a developer of an artificially intelligent-based SMS texting platform designed to bridge the conversation.
Hi Marley is a developer of an artificially intelligent-based SMS texting platform designed to bridge the conversation.
21
Funding: $41.3M
Sonde Health has developed a technology that uses voice biomarkers to identify a number of diseases such as respiratory disorders and mental illness.
Sonde Health has developed a technology that uses voice biomarkers to identify a number of diseases such as respiratory disorders and mental illness.
22
Funding: $35M
FDNA uses artificial intelligence to detect physiological patterns that reveal disease-causing genetic variations. With the world’s largest network of clinicians, labs and researchers creating one of the fastest growing and most comprehensive genomic databases, FDNA is changing the game for precision medicine.
FDNA uses artificial intelligence to detect physiological patterns that reveal disease-causing genetic variations. With the world’s largest network of clinicians, labs and researchers creating one of the fastest growing and most comprehensive genomic databases, FDNA is changing the game for precision medicine.
23
Funding: $32.1M
Make your products and services more intelligent with The Neurala Brain, a deep learning neural network software that mimics how the human brain works. Neurala is looking to put AI in the hands of toy makers, drone enthusiasts and IoT engineers alike.
Make your products and services more intelligent with The Neurala Brain, a deep learning neural network software that mimics how the human brain works. Neurala is looking to put AI in the hands of toy makers, drone enthusiasts and IoT engineers alike.
26
Funding: $17.2M
Filtered is a platform that helps companies hire better engineers based on ability, not resumes.
Filtered is a platform that helps companies hire better engineers based on ability, not resumes.
27
Funding: $16.5M
Orbita provides software to improve patient engagement in digital healthcare through voice-first and conversational AI solutions.
Orbita provides software to improve patient engagement in digital healthcare through voice-first and conversational AI solutions.
28
Funding: $13M
GenHealth.ai provides healthcare solutions using generative AI trained on encoded medical events.
GenHealth.ai provides healthcare solutions using generative AI trained on encoded medical events.
29
Funding: $5M
Open Source Agents for Developers. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles
Open Source Agents for Developers. Use AI to tackle the toil in your backlog, so you can focus on what matters: hard problems, creative challenges, and over-engineering your dotfiles
30
Funding: $300K
Endox develops physical-based articifial intelligence designed to perceive, adapt, and act in real time. Combining proprietary data acquisition technologies, next-generation robotics integration and edge-focused architectures, Endox creates systems scalable across various industries, including the US military.
Endox develops physical-based articifial intelligence designed to perceive, adapt, and act in real time. Combining proprietary data acquisition technologies, next-generation robotics integration and edge-focused architectures, Endox creates systems scalable across various industries, including the US military.
31
Funding: $120K
Cleo Robotics is developing a revolutionary new drone technology designed specifically for indoor applications. The company claims to incorporate a combination of stereo vision-based SLAM and neural networks for indoor navigation and obstacle avoidance.
Cleo Robotics is developing a revolutionary new drone technology designed specifically for indoor applications. The company claims to incorporate a combination of stereo vision-based SLAM and neural networks for indoor navigation and obstacle avoidance.
32
Funding: $100K
rStream Recycling pushes the limits of high-tech sustainability by leveraging recent advances in machine vision and novel hardware to automate waste sorting
rStream Recycling pushes the limits of high-tech sustainability by leveraging recent advances in machine vision and novel hardware to automate waste sorting
33
An AI tool that teachers can insert seamlessly into their existing workflows. The AI takes a topic and an optional reading and writes questions aligned to standards and learning outcomes.
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