Top 9 Artificial General Intelligence startups in USA

Sep 15, 2025 | By Siddhant Patel

1
Funding: $61.9B
OpenAI is an AI research and deployment company. Our mission is to ensure that artificial general intelligence benefits all of humanity.
2
Funding: $22.4B
xAI is an AI company that seeks to understand the true nature of the universe.
3
Funding: $20.7B
Anthropic is AI safety and research company that’s working to build reliable, interpretable, and steerable AI systems.
4
Funding: $3B
SSI is building safe superintelligence (SSI) - the most important technical problem of our​​ time.
5
Funding: $2B
Thinking Machines Lab is an artificial intelligence research and product company.
6
Funding: $276M
Hippocratic AI’s Aim is to develop the safest artificial Health General Intelligence (HGI).
7
Funding: $232M
Imbue is an independent research lab that trains foundational models to develop AI agents.
8

Numenta’s deep experience in theoretical neuroscience research has led to tremendous discoveries about how the brain works. We have developed a framework called the Thousand Brains Theory of Intelligence that will be fundamental to advancing the state of artificial intelligence and machine learning.
9

Primoria AI is building emotionally intelligent, adaptive AGI systems designed to evolve alongside users. Unlike traditional LLM tools, Primoria focuses on human-machine synergy, emotional context, and self-improving intelligence — shaping the next evolution of artificial intelligence.
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Editor: Siddhant Patel
Siddhant Patel is a senior editor for AI-Startups. He is based out of India and has previously worked at publications including Huffington Post and The Next Web. Siddhant has a special interest in artificial intelligence and has spent a decade covering the rapidly-evolving business and technology of the industry. Siddhant graduated from the Indian Institute of Science (Bengaluru). When he’s not writing, Siddhant is also a developer and has a deep historical knowledge of the computer industry for the past 50 years. You can contact Siddhant at sidpatel(at)ai-startups(dot)pro