Top 50 Startups developing AI for Medicine and Healthcare in USA
Apr 30, 2026
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26
1
Funding: $2.3B
Tempus is a technology company that is building the world's largest library of molecular and clinical data and an operating system to make that data accessible and to battle cancer.
Tempus is a technology company that is building the world's largest library of molecular and clinical data and an operating system to make that data accessible and to battle cancer.
2
Funding: $1.5B
Freenome has developed blood test for colorectal cancer detection based on artificial intelligence. Freenome's technology combines computational biology, machine learning and various data types to detect the most subtle signs of cancer, even in the earliest stages. In addition to colon cancer, the company is developing a test for lung cancer detection. Acquired by Perceptive Capital Solutions
Freenome has developed blood test for colorectal cancer detection based on artificial intelligence. Freenome's technology combines computational biology, machine learning and various data types to detect the most subtle signs of cancer, even in the earliest stages. In addition to colon cancer, the company is developing a test for lung cancer detection. Acquired by Perceptive Capital Solutions
3
Funding: $865.4M
Drug discovery, reimagined through Artificial Intelligence. We are discovering transformative new treatments by leveraging the speed of automation with the intelligence of computers. It’s drug discovery at unprecedented pace.
Drug discovery, reimagined through Artificial Intelligence. We are discovering transformative new treatments by leveraging the speed of automation with the intelligence of computers. It’s drug discovery at unprecedented pace.
4
Funding: $757.5M
Abridge is a medical conversation AI startup that offers an audio-based system to record and summarize medical conversations.
Abridge is a medical conversation AI startup that offers an audio-based system to record and summarize medical conversations.
6
Funding: $466.5M
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
Spring uses AI to help patients with mental health problems feel better faster. The startup operates as an online mental health clinic for employers, using proprietary machine-learning technology to provide personalized treatment recommendations with hopes that they will be more effective.
7
Funding: $457M
Metagenomi is using the power of metagenomics and machine learning to discover novel genome editing systems.
Metagenomi is using the power of metagenomics and machine learning to discover novel genome editing systems.
8
Funding: $418.7M
K Health has built the first HIPAA compliant AI health app 100% fueled by data, empowering users worldwide to take control of their health. By working with a unique data set of over a billion health interactions, K Health is able to generate better and more accurate insights based on PLM (a.k.a. “People Like Me”), a new approach to understanding our health that looks at other people like us who have had similar experiences.
K Health has built the first HIPAA compliant AI health app 100% fueled by data, empowering users worldwide to take control of their health. By working with a unique data set of over a billion health interactions, K Health is able to generate better and more accurate insights based on PLM (a.k.a. “People Like Me”), a new approach to understanding our health that looks at other people like us who have had similar experiences.
9
Funding: $402M
Hippocratic AI is developing a large-scale language model for healthcare and AI agents for patient interactions. These agents are not used for prescribing medications or making diagnoses, but rather for interacting with patients. The company focuses on its relentless to data security in order to earn trust of healthcare organizations and has partnerships with big hospitals, insurance and pharmaceutical companies.
Hippocratic AI is developing a large-scale language model for healthcare and AI agents for patient interactions. These agents are not used for prescribing medications or making diagnoses, but rather for interacting with patients. The company focuses on its relentless to data security in order to earn trust of healthcare organizations and has partnerships with big hospitals, insurance and pharmaceutical companies.
10
Funding: $394.3M
Absci is the drug & target discovery company harnessing deep learning AI & synthetic biology to expand the therapeutic potential of proteins
Absci is the drug & target discovery company harnessing deep learning AI & synthetic biology to expand the therapeutic potential of proteins
11
Funding: $387.5M
Caresyntax is a digital surgery platform that uses proprietary software and AI to deliver actionable insights to improve patient outcomes.
Caresyntax is a digital surgery platform that uses proprietary software and AI to deliver actionable insights to improve patient outcomes.
12
Funding: $355.2M
PathAI's goal is to improve cancer diagnosis using artificial intelligence. PathAI’s services solve the most challenging pathology problems faced by the research and pharmaceutical industry.
PathAI's goal is to improve cancer diagnosis using artificial intelligence. PathAI’s services solve the most challenging pathology problems faced by the research and pharmaceutical industry.
13
Funding: $328M
Clarify Health Solutions develops AI analytics software solutions that enable health systems to deliver more satisfying, better outcome and higher value care
Clarify Health Solutions develops AI analytics software solutions that enable health systems to deliver more satisfying, better outcome and higher value care
14
Funding: $324.9M
Flatiron Health is a healthcare technology and services company focused on accelerating cancer research and improving patient care. It uses machine-learning algorithms to analyse the world’s largest real-world oncology data source.
Flatiron Health is a healthcare technology and services company focused on accelerating cancer research and improving patient care. It uses machine-learning algorithms to analyse the world’s largest real-world oncology data source.
15
Funding: $300M
ConcertAI, a real-world data and artificial intelligence startup for healthcare providers and life science companies
ConcertAI, a real-world data and artificial intelligence startup for healthcare providers and life science companies
16
Funding: $295M
Immunai is a biotech company that combines single cell genomics with ML algorithms to enable high resolution profiling of the immune system.
Immunai is a biotech company that combines single cell genomics with ML algorithms to enable high resolution profiling of the immune system.
17
Funding: $291.6M
Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology.
Viz is a medical imaging company that helps optimize emergency treatment using deep learning technology.
18
Funding: $257.8M
Well Dot is an artificial intelligence startup that uses data and behavioral economics to provide daily health recommendations
Well Dot is an artificial intelligence startup that uses data and behavioral economics to provide daily health recommendations
19
Funding: $256.1M
Genesis Therapeutics unifies AI and biotech to accelerate the discovery of new medicines
Genesis Therapeutics unifies AI and biotech to accelerate the discovery of new medicines
20
Funding: $247M
Seismic Therapeutic is a biotechnology company advancing machine learning for immunology drug development.
Seismic Therapeutic is a biotechnology company advancing machine learning for immunology drug development.
21
Funding: $244.4M
InterVenn Biosciences combined the molecular-level resolution of mass spectrometry with the throughput of artificial intelligence to create a unique platform to discover new biomarkers, provide more effective treatments, design precision medicine trials, and pursue novel targets.
InterVenn Biosciences combined the molecular-level resolution of mass spectrometry with the throughput of artificial intelligence to create a unique platform to discover new biomarkers, provide more effective treatments, design precision medicine trials, and pursue novel targets.
22
Funding: $221.6M
Atomwise is the creator of AtomNet, the first Deep Learning technology for novel small molecule discovery, characterized by its unprecedented speed, accuracy, and diversity.
Atomwise is the creator of AtomNet, the first Deep Learning technology for novel small molecule discovery, characterized by its unprecedented speed, accuracy, and diversity.
23
Funding: $220M
Paige.AI, stands for Pathology AI Guidance Engine, is a new startup that uses artificial intelligence to fight cancer. The company focus on breast, prostrate and other major cancers, and expects to partner with other medical centers beyond MSK, as well as commercial labs and pharmaceutical companies as it grows and develops its applications.
Paige.AI, stands for Pathology AI Guidance Engine, is a new startup that uses artificial intelligence to fight cancer. The company focus on breast, prostrate and other major cancers, and expects to partner with other medical centers beyond MSK, as well as commercial labs and pharmaceutical companies as it grows and develops its applications.
24
Funding: $203M
Qventus is an AI-based software platform that solves operational challenges across the hospital including emergency departments, perioperative areas, and patient safety.
Qventus is an AI-based software platform that solves operational challenges across the hospital including emergency departments, perioperative areas, and patient safety.
25
Funding: $173.4M
IDx is a leading AI diagnostics company on a mission to transform the quality, accessibility, and affordability of healthcare. The company’s first product, IDx-DR, is an FDA-cleared AI-based diagnostic system designed for use at the front lines of care to detect diabetic retinopathy. IDx is developing additional AI-based diagnostic algorithms for the detection of macular degeneration, glaucoma, Alzheimer’s disease, cardiovascular disease, and stroke risk.
IDx is a leading AI diagnostics company on a mission to transform the quality, accessibility, and affordability of healthcare. The company’s first product, IDx-DR, is an FDA-cleared AI-based diagnostic system designed for use at the front lines of care to detect diabetic retinopathy. IDx is developing additional AI-based diagnostic algorithms for the detection of macular degeneration, glaucoma, Alzheimer’s disease, cardiovascular disease, and stroke risk.
26
Funding: $173.2M
Eko creates FDA approved software, AI, and heart sound and EKG sensors for heart disease monitoring.
Eko creates FDA approved software, AI, and heart sound and EKG sensors for heart disease monitoring.
28
Funding: $152.7M
nference Artificial Intelligence AI technology (nferX) enables Knowledge Synthesis from unstructured text & structured biomedical databases.
nference Artificial Intelligence AI technology (nferX) enables Knowledge Synthesis from unstructured text & structured biomedical databases.
29
Funding: $134.9M
Unlearn.AI accelerates drug development by pioneering computational clinical trials.
Unlearn.AI accelerates drug development by pioneering computational clinical trials.
30
Funding: $130.6M
Overjet combines deep learning of dental images and data science to empower dental providers and payers to deliver the best patient care.
Overjet combines deep learning of dental images and data science to empower dental providers and payers to deliver the best patient care.
31
Funding: $129.8M
Proscia makes digital pathology software and AI applications for cancer diagnosis.
Proscia makes digital pathology software and AI applications for cancer diagnosis.
32
Funding: $128M
Eleos Health is a mental health startup focused on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
Eleos Health is a mental health startup focused on using voice analysis and NLP to improve treatment outcomes and workflow efficiency.
33
Funding: $122.5M
Cellino is on a mission to make personalized, autologous stem cell therapies accessible for patients. Cellino’s platform combines label-free imaging and high-speed laser editing with machine learning to automate cell reprogramming
Cellino is on a mission to make personalized, autologous stem cell therapies accessible for patients. Cellino’s platform combines label-free imaging and high-speed laser editing with machine learning to automate cell reprogramming
34
Funding: $119.2M
Notable uses AI to automate and digitize every physician-patient interaction. It automtes recording of doctor’s visits and updating of electronic health records. The company has developed a technology that uses natural language processing and voice recognition to automatically record doctor-patient interactions and structure the data for inclusion in a patient’s medical records.
Notable uses AI to automate and digitize every physician-patient interaction. It automtes recording of doctor’s visits and updating of electronic health records. The company has developed a technology that uses natural language processing and voice recognition to automatically record doctor-patient interactions and structure the data for inclusion in a patient’s medical records.
35
Funding: $100M
RapidAI empowers clinicians to make faster, more accurate diagnostic and treatment decisions for stroke and aneurysm patients.
RapidAI empowers clinicians to make faster, more accurate diagnostic and treatment decisions for stroke and aneurysm patients.
36
Funding: $100.4M
Activ Surgical is building a hardware-agnostic platform to enable autonomous and collaborative surgery through the integration of computer vision, artificial intelligence and robotics.
Activ Surgical is building a hardware-agnostic platform to enable autonomous and collaborative surgery through the integration of computer vision, artificial intelligence and robotics.
37
Funding: $99.3M
BigHat Biosciences is a protein therapeutics company that develops an antibody design platform guided by artificial intelligence.
BigHat Biosciences is a protein therapeutics company that develops an antibody design platform guided by artificial intelligence.
38
Funding: $96M
Lantern Pharma is creating the AI platform RADR for the development of oncology drugs. It's mainly used to predict the potential response of patients to drugs. RADR uses publicly available databases, commercial clinical research and trial data, proprietary company data derived from ex vivo 3D tumor transcriptome models, genomic data and drug sensitivity data from a wide range of carefully selected sources that are constantly analyzed, tracked and updated. Currently, the Lantern Pharma's portfolio includes three leading drug candidates and an ADC program for the treatment of 12 oncological diseases, including non-small cell lung cancer (NSCLC), TNBC, Bladder Cancer, Recurrent Non-Hodgkins Lymphoma, select solid tumors
Lantern Pharma is creating the AI platform RADR for the development of oncology drugs. It's mainly used to predict the potential response of patients to drugs. RADR uses publicly available databases, commercial clinical research and trial data, proprietary company data derived from ex vivo 3D tumor transcriptome models, genomic data and drug sensitivity data from a wide range of carefully selected sources that are constantly analyzed, tracked and updated. Currently, the Lantern Pharma's portfolio includes three leading drug candidates and an ADC program for the treatment of 12 oncological diseases, including non-small cell lung cancer (NSCLC), TNBC, Bladder Cancer, Recurrent Non-Hodgkins Lymphoma, select solid tumors
39
Funding: $93.2M
The primary device of Current’s monitoring platform is an FDA-cleared upper-arm wearable that tracks skin temperature, pulse rate, oxygen saturation, movement and other metrics. It uses AI for precise early warning alerts.
The primary device of Current’s monitoring platform is an FDA-cleared upper-arm wearable that tracks skin temperature, pulse rate, oxygen saturation, movement and other metrics. It uses AI for precise early warning alerts.
40
Funding: $85.1M
Proprio uses machine learning, computer vision, and augmented reality user interfaces to improve the accuracy and efficiency of surgery.
Proprio uses machine learning, computer vision, and augmented reality user interfaces to improve the accuracy and efficiency of surgery.
41
Funding: $81.4M
Regard uses AI to automatically diagnose patients and generate accurate notes for doctors to improve patient care and reduce burnout.
Regard uses AI to automatically diagnose patients and generate accurate notes for doctors to improve patient care and reduce burnout.
42
Funding: $80.3M
Diligent Robotics builds AI-powered robot assistants that do humans' routine tasks. Moxi is our 1st commercial robot helping nurses.
Diligent Robotics builds AI-powered robot assistants that do humans' routine tasks. Moxi is our 1st commercial robot helping nurses.
43
Funding: $77.3M
GNS Healthcare is a big data analytics company that empowers health plans, providers, pharmaceutical companies, and foundations to make intelligent data-driven decisions. GNS provides the analytic solutions that specifically predict the impact of interventions for each individual to improve overall population health and reduce costs.
GNS Healthcare is a big data analytics company that empowers health plans, providers, pharmaceutical companies, and foundations to make intelligent data-driven decisions. GNS provides the analytic solutions that specifically predict the impact of interventions for each individual to improve overall population health and reduce costs.
44
Funding: $68.8M
AiCure's intelligent medical assistant, IMA, visually controls that medication is taken.
AiCure's intelligent medical assistant, IMA, visually controls that medication is taken.
45
Funding: $66.5M
Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.
Buoy is an AI-driven digital assistant that helps patients self-diagnose and triage to the appropriate care.
46
Funding: $65.4M
Mendel.ai automates matching cancer patients to clinical trials through personal medical history and genetic analysis.
Mendel.ai automates matching cancer patients to clinical trials through personal medical history and genetic analysis.
48
Funding: $59.2M
Subtle Medical develops AI empowered medical imaging workflow: faster, safer, and smarter
Subtle Medical develops AI empowered medical imaging workflow: faster, safer, and smarter
49
Funding: $47.4M
Eyenuk is a global digital health company and leader in real-world AI eye screening for autonomous disease detection
Eyenuk is a global digital health company and leader in real-world AI eye screening for autonomous disease detection
50
Funding: $42.7M
PreciseDx is the only Cancer Risk Stratification company to provide patient-specific risk information through the analysis of morphology.
PreciseDx is the only Cancer Risk Stratification company to provide patient-specific risk information through the analysis of morphology.
